eicosapentaenoic acid (EPA)
docosahexaenoic acid (DHA)
The omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are orthomolecular, conditionally essential nutrients that enhance quality of life and lower the risk of premature death. DHA is proven essential to pre- and postnatal brain development, whereas EPA seems more influential on behavior and mood. Both DHA and EPA generate neuroprotective metabolites. In double-blind, randomized, controlled trials, DHA and EPA combinations have been shown to benefit attention deficit/hyperactivity disorder (AD/HD), autism, dyspraxia, dyslexia, and aggression. For the affective disorders, meta-analyses confirm benefits in major depressive disorder (MDD) and bipolar disorder, with promising results in schizophrenia and initial benefit for borderline personality disorder. Accelerated cognitive decline and mild cognitive impairment (MCI) correlate with lowered tissue levels of DHA/EPA, and supplementation has improved cognitive function. Phosphatidylserine (contained in Lumonol) with DHA/EPA attached (Omega-3 PS) has been shown to alleviate AD/HD symptoms.1
Aside from the antidepressant and neuroprotective properties Omega-3s have been shown to possess, one recent landmark study found that aging humans who consumed more omega-3s had increased gray matter brain volume and that most new tissue development was observed in the part of the brain associated with happiness. Needlessly to say, Omega-3s is Key Brain Nutrient from the Cradle to the Grave.
Antioxidant Rich Vitamin E*
Vitamin E is a fat-soluble vitamin whose antioxidant properties plays an important role in protecting cells from the damaging effects of free radicals. According to the Linus Pauling Institute, there may be additional benefits to combining omega-3 fatty acids with an increased intake of vitamin E. This is because vitamin E can play an important role in preventing polyunsaturated fatty acids, such as those in fish oil, from becoming oxidized, or rancid. A study published in 2000 in "Medicine and Science in Sports and Exercise" concluded that vitamin E supplementation, when taken alongside fish oil, was able to reduce oxidative damage in rats. Fish oil may also reduce vitamin E levels in the body, which provides further reason to take the two together.†